Aspects of miRNAs as biomarkers in human diseases

نویسندگان

چکیده

RNA interference (RNAi) is one of the primary machineries involved in regulation gene expression using small double-stranded (dsRNA) eukaryotic cells. MicroRNA (miRNA) a class non-coding RNAs, regulating through canonical and non-canonical ways. Previous studies have shown that miRNA coding sequences make up 1% human genome currently 1917 miRNAs are displayed miRBase database. Expression levels circulating related to various pathophysiological conditions such as cancer, infectious conditions, cardiovascular diseases, neurodegenerative many more. Therefore, it important identify, detect analyse by silico experimental analyses. In this review, after brief description, we discuss use for diagnosis prognosis biomarkers biosensors addition miRNA-based therapies.

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ژورنال

عنوان ژورنال: International journal of science letters

سال: 2022

ISSN: ['2687-4733']

DOI: https://doi.org/10.38058/ijsl.1050036